The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2013

Filed:

Sep. 29, 2009
Applicants:

Yi-yuan Yang, Taipei, TW;

Hsueh-hsia Wu, Taipei, TW;

Sy-jye Leu, Taipei, TW;

Neng-yao Shih, Miaoli County, TW;

I-jen Huang, Tainan, TW;

Wen-shyang Hsieh, Taipei, TW;

Ko-jiunn Liu, Miaoli County, TW;

Shih-yi Huang, Taipei, TW;

Yung-luen Shih, Taipei, TW;

Chi-hsin Lee, Taipei, TW;

Yuan-soon Ho, Taipei, TW;

Shih-lan Hsu, Taipei, TW;

Inventors:

Yi-Yuan Yang, Taipei, TW;

Hsueh-Hsia Wu, Taipei, TW;

Sy-Jye Leu, Taipei, TW;

Neng-Yao Shih, Miaoli County, TW;

I-Jen Huang, Tainan, TW;

Wen-Shyang Hsieh, Taipei, TW;

Ko-Jiunn Liu, Miaoli County, TW;

Shih-Yi Huang, Taipei, TW;

Yung-Luen Shih, Taipei, TW;

Chi-Hsin Lee, Taipei, TW;

Yuan-Soon Ho, Taipei, TW;

Shih-Lan Hsu, Taipei, TW;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 39/02 (2006.01); A61K 39/112 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method for the treatment and/or prevention of bacterial infection caused by Enterobacteriaceae bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation in a mammal. An antibody and a kit on the basis of the vaccinating method and detecting/diagnosing method are also provided.


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