The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2013
Filed:
Jul. 21, 2008
Wenjie Mei, Guangzhou, CN;
Wenjie Mei, Guangzhou, CN;
Guangdong Pharmaceutical University, Guangdong, CN;
Abstract
The invention is reported a type of chair ruthenium complexes and their used as anticancer agent. The general formulae of these chair ruthenium complexes is: A-[Ru(bpy)L](PF), where in A is Δ or Λ, L is tFPIP, IPBP, IPBH or PYNI. These chair ruthenium complexes is characterized with that the center atom is ruthenium ion, the main ligand is 2-phenyl imidazole[4,5][1,10]phenanthroline and its derivate, the co-ligand is two bipyridine, and the space structure is rigid octahedral. The complexes indicated by the invention are the chair isomer of all of these ruthenium complexes. This type of ruthenium complexes exhibit excellent inhibitory activity against liver cancer cell line BEL-7402, and can be used in preparing anticancer agent.