The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2013

Filed:

Sep. 01, 2005
Applicants:

Petr Cankar, Olomouc, CZ;

Iveta Frysova, Mohelnice, CZ;

Vladimir Krystof, Olomouc, CZ;

Rene Lenobel, Sternberk, CZ;

Jan Slouka, Olomouc, CZ;

Miroslav Strnad, Olomouc, CZ;

Peter Martin Fischer, Beeston, GB;

Inventors:

Petr Cankar, Olomouc, CZ;

Iveta Frysova, Mohelnice, CZ;

Vladimir Krystof, Olomouc, CZ;

Rene Lenobel, Sternberk, CZ;

Jan Slouka, Olomouc, CZ;

Miroslav Strnad, Olomouc, CZ;

Peter Martin Fischer, Beeston, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/655 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); C07D 231/38 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A series of mono- and binuclear 4-arylazo-3,5-diamino-pyrazoles which are useful for inhibition of cyclin-dependent kinases (preferably CDK9). Hence they can be used as antimitotic-, pro-apoptotic and antiinflammatory drugs, in particular, in chemotherapy of cancer and asthma, therapy of psoriasis and parasitoses as those caused by fungi or protists, treatment of Alzheimer's disease or as antineurodegenerative drugs, or to suppress immunostimulation. These compounds are useful in a variety of utilities, including as intermediates in the preparation of flame-retardants, diagnostic reagents and therapeutics, including antivirals and immunosuppressors.


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