The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2013

Filed:

Mar. 27, 2008
Applicants:

Alahari Arunakumari, Pennington, NJ (US);

Xiao-ping Dai, Bloomsbury, NJ (US);

Haile Ghebramariam, Easton, PA (US);

Inventors:

Alahari Arunakumari, Pennington, NJ (US);

Xiao-Ping Dai, Bloomsbury, NJ (US);

Haile Ghebramariam, Easton, PA (US);

Assignee:

Medarex, Inc., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are methods relating to amplification and expression of a nucleic acid sequence encoding a polypeptide of interest in recombinant cells, and cell lines and polypeptides produced from such methods. The methods disclosed herein permit the amplification of cell lines that express a polypeptide of interest in a relatively short period of time through the use of a bioreactor.


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