The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2013
Filed:
Jun. 12, 2008
Michael Burnet, Kusterdingen, DE;
Jan-hinrich Guse, Tübingen-Buhl, DE;
Gene Kim, Tübingen, DE;
Albert Beck, Nehren, DE;
Georgia Tsotsou, Tuebingen, DE;
Irina Droste-borel, Tuebingen, DE;
Laurence Barker, Tübingen, DE;
Michael Wolff, Kusterdingen, DE;
Hans-jurgen Gutke, Stuttgart, DE;
Michael Burnet, Kusterdingen, DE;
Jan-Hinrich Guse, Tübingen-Buhl, DE;
Gene Kim, Tübingen, DE;
Albert Beck, Nehren, DE;
Georgia Tsotsou, Tuebingen, DE;
Irina Droste-Borel, Tuebingen, DE;
Laurence Barker, Tübingen, DE;
Michael Wolff, Kusterdingen, DE;
Hans-Jurgen Gutke, Stuttgart, DE;
Other;
Abstract
This invention features a method of identifying a compound useful for enhancing efficacy of a therapeutic agent. The method includes incubating a compound in blood cells; separating immune cells from erythrocytic cells; and determining the ratio of the concentration of the compound in the immune cells to the concentration of the compound in the erythrocytic cells; wherein the compound comprises a transportophore and a therapeutic agent, in which the transportophore is covalently bonded to the therapeutic agent via a bond or a linker.