The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2013
Filed:
Sep. 24, 2007
Louis Bonhomme, Waltham, MA (US);
John Doyle, Kensington, NH (US);
Kurt Greenizen, Bradford, MA (US);
George Gagne, Dracut, MA (US);
Sean Devin, Dublin Pike, IE;
Gerard Lombard, Ballyhooley, IE;
Vincent Smith, Ballincollig, IE;
Mark Kavonian, North Reading, MA (US);
Louis Bonhomme, Waltham, MA (US);
John Doyle, Kensington, NH (US);
Kurt Greenizen, Bradford, MA (US);
George Gagne, Dracut, MA (US);
Sean Devin, Dublin Pike, IE;
Gerard Lombard, Ballyhooley, IE;
Vincent Smith, Ballincollig, IE;
Mark Kavonian, North Reading, MA (US);
EMD Millipore Corporation, Billerica, MA (US);
Abstract
Filtration device suited for concentration of liquid samples, particularly biomolecules, and a method of concentrating, desalting, purifying and/or fractionating liquid samples. In certain embodiments the device includes a housing having a sample reservoir, and two substantially vertically oriented and spaced apart membranes disposed in the housing. An underdrain is associated with each membrane such that fluid passing through each membrane flows through a respective underdrain into a filtrate collection chamber. The fluid that does not pass through the membrane is collected in the retentate collection chamber, and can be recovered such as by a reverse spinning step, achieving recoveries greater than about 90%. The substantially vertical orientation of the membranes increases the available membrane area by at least 2.7 times the area available in a conventional filter device. The two-panel configuration also maintains more available membrane area in use during the last stages of filtration than a one-panel configuration.