The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2013

Filed:

Feb. 09, 2010
Applicants:

David Joseph Bartkovitz, Nutley, NJ (US);

Xin-jie Chu, Livingston, NJ (US);

Qingjie Ding, Bridgewater, NJ (US);

Nan Jiang, Pine Brook, NJ (US);

Jin-jun Liu, Warren Township, NJ (US);

Tina Morgan Ross, Royersford, PA (US);

Jing Zhang, Parsippany, NJ (US);

Zhuming Zhang, Hillsborough, NJ (US);

Inventors:

David Joseph Bartkovitz, Nutley, NJ (US);

Xin-Jie Chu, Livingston, NJ (US);

Qingjie Ding, Bridgewater, NJ (US);

Nan Jiang, Pine Brook, NJ (US);

Jin-Jun Liu, Warren Township, NJ (US);

Tina Morgan Ross, Royersford, PA (US);

Jing Zhang, Parsippany, NJ (US);

Zhuming Zhang, Hillsborough, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); C07D 207/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are provided compounds of the formula wherein X, Y, R, R, R, R, R, R, Rand Rare as described hereinand enantiomers and pharmaceutically acceptable salts and esters thereof. The compounds are useful as anticancer agents.


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