The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2013
Filed:
Jan. 30, 2009
Andrei Gennadyevich Fadeev, Elmira, NY (US);
Jennifer Gehman, Painted Post, NY (US);
Zara Melkoumian, Painted Post, NY (US);
David Michael Weber, Corning, NY (US);
Yue Zhou, Horseheads, NY (US);
Andrei Gennadyevich Fadeev, Elmira, NY (US);
Jennifer Gehman, Painted Post, NY (US);
Zara Melkoumian, Painted Post, NY (US);
David Michael Weber, Corning, NY (US);
Yue Zhou, Horseheads, NY (US);
Geron Corporation, Menlo Park, CA (US);
Abstract
Synthetic surfaces capable of supporting culture of eukaryotic cells including stem cells and undifferentiated human embryonic stem cells in a chemically defined medium include a swellable (meth)acrylate layer and a polypeptide conjugated to the swellable (meth)acrylate layer. The swellable (meth)acrylate layer may be formed by polymerizing monomers in a composition that includes a carboxyl group-containing (meth)acrylate monomer, a cross-linking (di- or higher-functional) (meth)acrylate monomer, and a hydrophilic monomer capable of polymerizing with the carboxyl group-containing (meth)acrylate monomer and the cross-linking (meth)acrylate monomer. The swellable (meth)acrylate layer has an equilibrium water content in water of between about 5% and about 70%. The conjugated peptide may include an RGD amino acid sequence.