The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2013
Filed:
Jun. 13, 2008
Applicants:
Yusuke Nakamura, Tokyo, JP;
Yoichi Furukawa, Tokyo, JP;
Ryuji Hamamoto, Tokyo, JP;
Shuichi Nakatsuru, Kanagawa, JP;
Inventors:
Yusuke Nakamura, Tokyo, JP;
Yoichi Furukawa, Tokyo, JP;
Ryuji Hamamoto, Tokyo, JP;
Shuichi Nakatsuru, Kanagawa, JP;
Assignee:
Oncotherapy Science, Inc., Kanagawa, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to methods for determining the methyltransferase activity of a polypeptide and screening for modulators of methyltransferase activity, more particularly for modulators of the methylation of VEGFR1 by SMYD3. The invention further provides methods and pharmaceutical compositions for treating and preventing colorectal cancer, hepatocellular carcinoma, bladder cancer and/or breast cancer using a modulator so identified.