The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2013
Filed:
Oct. 19, 2009
Wei LI, Wuhan, CN;
Guofan Xie, Wuhan, CN;
Jianzhong Zhou, Wuhan, CN;
BO Yang, Wuhan, CN;
Zhiqiang Qian, Wuhan, CN;
Yan Chen, Wuhan, CN;
Haiming Geng, Wuhan, CN;
Jianming Zhou, Wuhan, CN;
LU Huang, Wuhan, CN;
Wei Li, Wuhan, CN;
Guofan Xie, Wuhan, CN;
Jianzhong Zhou, Wuhan, CN;
Bo Yang, Wuhan, CN;
Zhiqiang Qian, Wuhan, CN;
Yan Chen, Wuhan, CN;
Haiming Geng, Wuhan, CN;
Jianming Zhou, Wuhan, CN;
Lu Huang, Wuhan, CN;
Grand Pharma (China) Co., Ltd., Wuhan, CN;
Abstract
A method of preparation of 5,6-dimethylxanthone-4-acetic acid (DMXAA) and derivatives thereof. The derivatives are represented by formula (I), wherein R represents totally 1 to 2 substitutes at 1, 2, 3, 7, and 8 position selected from a lower alkyl, halogen, CF, CN, NO, NH, CHCOOH, OR, OH, NHSOR, SR, CHCONHRor NHR, and Rrepresents a lower alkyl, or a lower alkyl having OH, NH, or OCH. The invention further provides a pharmaceutical composition having such derivatives used as excellent antitumor and antibacterial agents.