The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2013

Filed:

Dec. 05, 2008
Applicants:

Tim Hugo Maria Jonckers, Mechelen, BE;

Wim Bert Griet Schepens, Mechelen, BE;

Geerwin Yvonne Paul Haché, Mechelen, BE;

Beate Sabine Hallenberger, Mechelen, BE;

Jennifer Chiyomi Sasaki, Mechelen, BE;

Judith Eva Baumeister, Mechelen, BE;

Gerben Albert Van 't Klooster, Mechelen, BE;

Inventors:
Assignee:

Janssen R&D Ireland, Little Island, IE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 277/62 (2006.01); C07D 277/30 (2006.01); C07D 261/20 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds that have CYP450 inhibiting properties and are therefore useful as boosters of certain drugs, i.e. they are able to increase at least one of the pharmacokinetic variables of certain drugs when co-administered. The invention further provides the use of said compounds as improvers of the bioavailability of certain drugs. Methods for the preparation of the compounds of the invention and pharmaceutical compositions are also provided.


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