The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2013

Filed:

Feb. 07, 2011
Applicants:

Nigel C. Phillips, Pointe-Claire, CA;

Mario C. Filion, Laval, CA;

Zdenek Richard Holan, Montreal, CA;

Stephanie Reader, Ste-Julie, CA;

Inventors:

Nigel C. Phillips, Pointe-Claire, CA;

Mario C. Filion, Laval, CA;

Zdenek Richard Holan, Montreal, CA;

Stephanie Reader, Ste-Julie, CA;

Assignee:

Bioniche Life Sciences Inc., Belleville, Ontario, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel synthetic oligonucleotide sequences (hereinafter sequence) of 3 to 9 bases in length comprising one or more non-DNA bases wherein the bases are nebularine, hypoxanthine, or uracil, or combinations of nebularine, hypoxanthine and uracil bases. These sequences optionally further comprise one or more guanine bases or one or more thymine bases, or combinations thereof. The present invention also provides methods of using these compositions to induce responses in cells, and to treat diseases and conditions characterized by undesired cellular proliferation such as autoimmune disease, lymphoproliferative disease, inflammation or cancer.


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