The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2013
Filed:
Jun. 28, 2011
Anan Chuntharapai, Colma, CA (US);
Gregory D. Plowman, San Carlos, CA (US);
Marc Tessier-lavigne, Woodside, CA (US);
Yan Wu, Foster City, CA (US);
Weilan YE, Foster City, CA (US);
Anan Chuntharapai, Colma, CA (US);
Gregory D. Plowman, San Carlos, CA (US);
Marc Tessier-Lavigne, Woodside, CA (US);
Yan Wu, Foster City, CA (US);
Weilan Ye, Foster City, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.