The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8349893 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 08, 2013

Filed:

Apr. 28, 2009
Applicants:

Mirjana Andjelkovic, Basel, CH;

Simona M. Ceccarelli, Basel, CH;

Odile Chomienne, Altkirch, FR;

Patrizio Mattei, Riehen, CH;

Inventors:

Mirjana Andjelkovic, Basel, CH;

Simona M. Ceccarelli, Basel, CH;

Odile Chomienne, Altkirch, FR;

Patrizio Mattei, Riehen, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/205 (2006.01); C07C 229/04 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to novel 4-trimethylammoniobutyrates of the formula wherein A, R, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments.


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