The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2013
Filed:
Oct. 06, 2009
Michael David Bentley, Huntsville, AL (US);
Michael James Roberts, Williamsburg, VA (US);
Xiaoming Shen, Madison, AL (US);
Lin Cheng, Huntsville, AL (US);
Michael David Bentley, Huntsville, AL (US);
Michael James Roberts, Williamsburg, VA (US);
Xiaoming Shen, Madison, AL (US);
Lin Cheng, Huntsville, AL (US);
Nektar Therapeutics, San Francisco, CA (US);
Abstract
The invention provides polymer conjugates of opioid antagonists comprising a polymer, such as poly(ethylene glycol), covalently attached to an opioid antagonist. The linkage between the polymer and the opioid antagonist is preferably hydrolytically stable. The invention also includes a method of treating one or more side effects associated with the use of opioid analgesics, such as constipation, nausea, or pruritus, by administering a polymer conjugate of the invention.