The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2013

Filed:

Jun. 08, 2009
Applicants:

Michelle Machacek, Brookline, MA (US);

Gabriela DE Almeida, Brookline, MA (US);

Jonathan B. Grimm, Newton, MA (US);

Rachel N. Maccoss, Brookline, MA (US);

Eric Romeo, Allston, MA (US);

Tony Siu, Brookline, MA (US);

Catherine White, Newton Center, LA (US);

Kevin Wilson, West Newton, MA (US);

Inventors:

Michelle Machacek, Brookline, MA (US);

Gabriela de Almeida, Brookline, MA (US);

Jonathan B. Grimm, Newton, MA (US);

Rachel N. MacCoss, Brookline, MA (US);

Eric Romeo, Allston, MA (US);

Tony Siu, Brookline, MA (US);

Catherine White, Newton Center, LA (US);

Kevin Wilson, West Newton, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/02 (2006.01); A61K 31/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3, TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.


Find Patent Forward Citations

Machacek, Michelle. (2013). Inhibitors of janus kinases (U.S. Patent No. 8344144). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8344144

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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