The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2013
Filed:
Aug. 02, 2010
Edward T. Kisak, San Diego, CA (US);
John M. Newsam, La Jolla, CA (US);
Dominic King-smith, San Diego, CA (US);
Pankaj Karande, Troy, NY (US);
Samir Mitragotri, Goleta, CA (US);
Edward T. Kisak, San Diego, CA (US);
John M. Newsam, La Jolla, CA (US);
Dominic King-Smith, San Diego, CA (US);
Pankaj Karande, Troy, NY (US);
Samir Mitragotri, Goleta, CA (US);
Nuvo Research Inc., Mississagua, Ontario, CA;
Abstract
It has been discovered that certain combinations compounds are excellent penetration enhancers and, as such, can be incorporated in a topical formulation to facilitate administration of active agents. The increased penetration enhancement can also lead to a reduction in the total concentration of skin irritants in the formulation. There is described herein a topical formulation comprising (i) at least one active agent; (ii) a first compound, and (iii) a second compound, wherein the first compound and second compound are different, and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate and sodium lauryl sulfoacetate.