The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2013
Filed:
Dec. 11, 2009
Nicholas Pomato, Frederick, MD (US);
Martin V. Haspel, Seneca, MD (US);
Janet H. Ransom, North Potomac, MD (US);
Nicholas Pomato, Frederick, MD (US);
Martin V. Haspel, Seneca, MD (US);
Janet H. Ransom, North Potomac, MD (US);
Intracel Holdings LLC, Frederick, MD (US);
Abstract
This invention providesantitoxin compositions and methods of production, and methods of treating animals and humans prophylactically and also those suspected of having contacted botulism toxin. Theantitoxin is prepared by inoculating an animal with a monovalenttoxoid and toxin. The animal's plasma is collected and purified at a high pH by affinity chromatography. The resulting monovalent immunoglobulins are de-speciated by digestion with pepsin. Monovalent antitoxins for all sevenserotypes are then combined to produce a high titered heptavalentantitoxin composition.