The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2013
Filed:
Mar. 13, 2012
Applicants:
David Baker, San Diego, CA (US);
Louis H. Bookbinder, San Diego, CA (US);
Inventors:
David Baker, San Diego, CA (US);
Louis H. Bookbinder, San Diego, CA (US);
Assignee:
Halozyme, Inc., San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); A61K 38/54 (2006.01); A61K 48/00 (2006.01); C12P 21/06 (2006.01); C12N 9/24 (2006.01); C12N 9/26 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided are methods for preparing culture medium that contains soluble hyaluronidases. The methods employ cells that contain a plurality of active copies of nucleic acid encoding the soluble hyaluronidase and a plurality of feedings and temperature changes, whereby the encoded soluble hyaluronidase is secreted into the cell culture medium.