The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2012

Filed:

Feb. 20, 2008
Applicants:

Fortune Kohen, Tel Aviv, IL;

Dalia Somjen, Rehovot, IL;

Naftali Stern, Nir Zvi, IL;

Veronica Frydman, Rehovot, IL;

Tikva Kulik, Rehovot, IL;

Batya Gayer, Rehovot, IL;

Inventors:

Fortune Kohen, Tel Aviv, IL;

Dalia Somjen, Rehovot, IL;

Naftali Stern, Nir Zvi, IL;

Veronica Frydman, Rehovot, IL;

Tikva Kulik, Rehovot, IL;

Batya Gayer, Rehovot, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/30 (2006.01); C07H 15/26 (2006.01); A61K 31/7048 (2006.01); A61K 31/352 (2006.01);
U.S. Cl.
CPC ...
Abstract

Isoflavone derivatives are provided comprising a carboxyalkylene moiety linked via its alkylene chain to the aromatic ring and via its carboxy group to an aminoalkyleneamino residue, which, in turn, is covalently linked to a functional group B. The isoflavone derivatives are preferably derived from biochanin A, genistein, and daidzein, and the functional group B is preferably an amino protecting group. These isoflavone derivatives are useful for treating or preventing diseases or disorders associated with estrogen receptor functioning.


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