The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Aug. 20, 2009
Jinbo Lee, Andover, MA (US);
Julian F. Bond, Weymouth, MA (US);
Nicholas Terrett, Sherborn, MA (US);
Frank G. Favaloro, Jr., North Attleboro, MA (US);
Daniel Wang, Duxbury, MA (US);
Timothy F. Briggs, Cambridge, MA (US);
Benjamin Adam Seigal, Watertown, MA (US);
Wei-chuan Sun, Menlo Park, CA (US);
Stephen P. Hale, Belmont, MA (US);
Jinbo Lee, Andover, MA (US);
Julian F. Bond, Weymouth, MA (US);
Nicholas Terrett, Sherborn, MA (US);
Frank G. Favaloro, Jr., North Attleboro, MA (US);
Daniel Wang, Duxbury, MA (US);
Timothy F. Briggs, Cambridge, MA (US);
Benjamin Adam Seigal, Watertown, MA (US);
Wei-Chuan Sun, Menlo Park, CA (US);
Stephen P. Hale, Belmont, MA (US);
Ensemble Therapeutics Corporation, Cambridge, MA (US);
Abstract
Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.