The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Apr. 29, 2011
Huanming Chen, Irvine, CA (US);
Jean-michel Vernier, Laguna Niguel, CA (US);
Huanming Chen, Irvine, CA (US);
Jean-Michel Vernier, Laguna Niguel, CA (US);
Valeant Pharmaceuticals International, Inc., Aliso Viejo, CA (US);
Abstract
This invention provides compounds of formula I where Aris a 5- to 10-member mono- or bicyclic aromatic group, optionally substituted; where the —NRRgroup is situated ortho to the NHC(═X) group; n=1 or 2; X=O or S; Y is O or S; and q=1 or 0. The invention also provides pharmaceutical compositions comprising compounds of formula I and/or salts, esters, and prodrugs thereof. These compounds modulate the activation and inactivation of potassium channels. The compounds are useful for the treatment and prevention of diseases and disorders—such as seizure disorders—which are affected by modulation of potassium ion channels.