The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Jan. 04, 2011
Christina Marie Coughlin, Berwyn, PA (US);
Jay Marshall Feingold, Wynnewood, PA (US);
Daniel Stephen Johnston, Trappe, PA (US);
Anna Berkenblit, Needham, MA (US);
Andrew Louis Strahs, Maynard, MA (US);
Charles Michael Zacharchuk, Westford, MA (US);
Christina Marie Coughlin, Berwyn, PA (US);
Jay Marshall Feingold, Wynnewood, PA (US);
Daniel Stephen Johnston, Trappe, PA (US);
Anna Berkenblit, Needham, MA (US);
Andrew Louis Strahs, Maynard, MA (US);
Charles Michael Zacharchuk, Westford, MA (US);
Wyeth LLC, Madison, NJ (US);
Abstract
A cut-point in the quantitative measurement of PTEN protein expression that accurately identifies tumors with two inactivated alleles of the PTEN gene. Patients with a normalized PTEN score of PTEN null will be treated with a pan-ErbB tyrosine kinase inhibitor. A normalized PTEN protein expression score is obtained by comparing the tumor PTEN OD expression value with the non-malignant PTEN OD expression value.