The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Jun. 20, 2007
Piet André Maurits Maria Herdewijn, Rotselaar/Wezemaal, BE;
Steven Cesar Alfons DE Jonghe, Brussels, BE;
William John Watkins, Saratoga, CA (US);
Lee Shun Chong, Newark, CA (US);
Jennifer Zhang, Foster City, CA (US);
Piet André Maurits Maria Herdewijn, Rotselaar/Wezemaal, BE;
Steven Cesar Alfons De Jonghe, Brussels, BE;
William John Watkins, Saratoga, CA (US);
Lee Shun Chong, Newark, CA (US);
Jennifer Zhang, Foster City, CA (US);
Gilead Sciences, Inc., Foster City, CA (US);
Abstract
This invention provides di-, tri- and tetra-substituted pyrido(3,2-d)pyrimidine derivatives with specific substituting patterns, their pharmaceutically acceptable salts, N-oxides, solvates, pro-drugs and enantiomers, possessing unexpectedly desirable pharmaceutical properties, in particular being highly active antiviral agents. The invention also provides use of such derivatives in the treatment of viral infections and pathologic conditions associated therewith, including hepatitis C.