The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Aug. 02, 2011
Sérgio Luiz Sacurai, São Paulo, BR;
Márcio Henrique Zaim, São Paulo, BR;
Carlos Eduardo Da Costa Touzarim, São Paulo, BR;
Artur Franz Keppler, São Paulo, BR;
Gilberto DE Nucci, São Paulo, BR;
Sérgio Luiz Sacurai, São Paulo, BR;
Márcio Henrique Zaim, São Paulo, BR;
Carlos Eduardo da Costa Touzarim, São Paulo, BR;
Artur Franz Keppler, São Paulo, BR;
Gilberto De Nucci, São Paulo, BR;
Biolab Sanus Farmaceutica Ltda., Vila Olimpia, Sao Paulo, BR;
Abstract
A series of derivatives of 6,7-dihydro-3H-oxazolo[3,4-a]pyrazine-5,8-dione, mixtures thereof, their pharmaceutically acceptable salts, which are inhibitors of PDE-5, possessing vasodilatator properties and relaxing effects. In particular, compounds of formula (I), where R, R, R, and Rare defined herein, processes for the preparation of said compounds, pharmaceutical compositions containing them, as well as uses as inhibitors of the enzyme phosphodiesterase type 5 (PDE-5) in the treatment of the erectile dysfunction and PDE-5 inhibitor treatable disorders.