The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Jun. 27, 2008
Ángel Pey Rodríguez, Zaragoza, ES;
Aurora Martínez Ruiz, Zaragoza, ES;
Javier Sancho Sanz, Zaragoza, ES;
Nunilo Cremades Casasín, Zaragoza, ES;
Adrián Velázquez Campoy, Zaragoza, ES;
Ming Ying, Zaragoza, ES;
Ángel Pey Rodríguez, Zaragoza, ES;
Aurora Martínez Ruiz, Zaragoza, ES;
Javier Sancho Sanz, Zaragoza, ES;
Nunilo Cremades Casasín, Zaragoza, ES;
Adrián Velázquez Campoy, Zaragoza, ES;
Ming Ying, Zaragoza, ES;
Universidad de Zaragoza, Zaragoza, ES;
Abstract
The present invention relates to the use of specific types of compounds acting as pharmacological chaperones having a stabilizing activity on the phenylalanine hydroxylase (PAH) enzyme for the prophylaxis and/or treatment of hyperphenylalaninemia (HPA) and phenylketonuria PKU) and diseases, disorders and conditions related thereto. Further, the present invention relates to pharmaceutical compositions containing the compounds according to the present invention as well as to methods of treatment of HPA, in particular, PKU and diseases, disorders and conditions related thereto.