The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Nov. 17, 2011
Seok-ki Choi, Ann Arbor, MI (US);
Paul R. Fatheree, San Francisco, CA (US);
Roland Gendron, San Francisco, CA (US);
Robert Murray Mckinnell, Millbrae, CA (US);
Brooke Blair, San Francisco, CA (US);
Seok-ki Choi, Ann Arbor, MI (US);
Paul R. Fatheree, San Francisco, CA (US);
Roland Gendron, San Francisco, CA (US);
Robert Murray McKinnell, Millbrae, CA (US);
Brooke Blair, San Francisco, CA (US);
Theravance, Inc., South San Francisco, CA (US);
Abstract
In one aspect, the invention relates to compounds having the formula: wherein: Ar, r, Z, X, R, and Rare as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have ATreceptor antagonist activity and neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.