The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
May. 13, 2011
Guy W. Bemis, Arlington, MA (US);
Francesco G. Salituro, Marlborough, MA (US);
John P. Duffy, Northborough, MA (US);
John E. Cochran, North Andover, MA (US);
Edmund M. Harrington, South Boston, MA (US);
Mark A. Murcko, Holliston, MA (US);
Keith P. Wilson, Hopkinton, MA (US);
Michael Su, Newton, MA (US);
Vincent P. Galullo, Watertown, MA (US);
Guy W. Bemis, Arlington, MA (US);
Francesco G. Salituro, Marlborough, MA (US);
John P. Duffy, Northborough, MA (US);
John E. Cochran, North Andover, MA (US);
Edmund M. Harrington, South Boston, MA (US);
Mark A. Murcko, Holliston, MA (US);
Keith P. Wilson, Hopkinton, MA (US);
Michael Su, Newton, MA (US);
Vincent P. Galullo, Watertown, MA (US);
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Abstract
The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.