The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2012

Filed:

Mar. 27, 2009
Applicants:

Jian Chen, Princeton, NJ (US);

Ellen Filvaroff, San Francisco, CA (US);

Sherman Fong, Alameda, CA (US);

Audrey Goddard, San Francisco, CA (US);

Paul Godowski, Burlingame, CA (US);

J. Christopher Grimaldi, San Francisco, CA (US);

Austin Gurney, Belmont, CA (US);

Hanzhong LI, San Mateo, CA (US);

Kenneth Hillan, San Francisco, CA (US);

Sarah G. Hymowitz, San Francisco, CA (US);

Daniel Tumas, Orinda, CA (US);

Melissa A. Starovasnik, San Francisco, CA (US);

Menno Vanlookeren, San Francisco, CA (US);

Richard Vandlen, Hillsborough, CA (US);

Colin Watanabe, Moraga, CA (US);

P. Mickey Williams, Half Moon Bay, CA (US);

William I. Wood, Hillsborough, CA (US);

Daniel Yansura, Pacifica, CA (US);

Inventors:

Jian Chen, Princeton, NJ (US);

Ellen Filvaroff, San Francisco, CA (US);

Sherman Fong, Alameda, CA (US);

Audrey Goddard, San Francisco, CA (US);

Paul Godowski, Burlingame, CA (US);

J. Christopher Grimaldi, San Francisco, CA (US);

Austin Gurney, Belmont, CA (US);

Hanzhong Li, San Mateo, CA (US);

Kenneth Hillan, San Francisco, CA (US);

Sarah G. Hymowitz, San Francisco, CA (US);

Daniel Tumas, Orinda, CA (US);

Melissa A. Starovasnik, San Francisco, CA (US);

Menno VanLookeren, San Francisco, CA (US);

Richard Vandlen, Hillsborough, CA (US);

Colin Watanabe, Moraga, CA (US);

P. Mickey Williams, Half Moon Bay, CA (US);

William I. Wood, Hillsborough, CA (US);

Daniel Yansura, Pacifica, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.


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