The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2012
Filed:
Apr. 03, 2008
Applicants:
Ana P. Goncalvez, Rockville, MD (US);
Robert H. Purcell, Gaithersburg, MD (US);
Ching-juh Lai, Bethesda, MD (US);
Inventors:
Ana P. Goncalvez, Rockville, MD (US);
Robert H. Purcell, Gaithersburg, MD (US);
Ching-Juh Lai, Bethesda, MD (US);
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/42 (2006.01); A61K 39/12 (2006.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to a variant of a parent polypeptide comprising an Fc region, which variant binds an Fc gamma receptor (FcγR) with lower affinity than the parent polypeptide and comprises a deletion of at least one amino acid in about position 100 to about position 150 in the Fc region and related nucleic acids, vectors, host cells and methods of producing the variant and methods for preventing or treating a disorder in a mammal.