The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2012

Filed:

Apr. 12, 2010
Applicants:

Clay F. Semenkovich, Ladue, MO (US);

Manu V. Chakravarthy, Scotch Plains, NJ (US);

John W. Turk, Eureka, MO (US);

Inventors:

Clay F. Semenkovich, Ladue, MO (US);

Manu V. Chakravarthy, Scotch Plains, NJ (US);

John W. Turk, Eureka, MO (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/44 (2006.01); A61K 31/685 (2006.01); G01N 33/48 (2006.01); G01N 33/92 (2006.01); A01N 43/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions comprising the peroxisome proliferator-activated receptor alpha (PPARα)-ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC) are disclosed. These compositions may be used for the prophylaxis and treatment of PPARα-related liver disorders including, but not necessarily limited to, fatty liver disease, to lower lipid and triglyceride levels, and to increase high density lipoprotein levels in animals. Foods modified with 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1GPC) may be used to improve the metabolism of animals.


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