The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2012

Filed:

May. 15, 2006
Applicants:

Benjamin James Boyd, Warrandyte, AU;

Lisa Michelle Kaminskas, Brunswick West, AU;

Christopher John Hamilton Porter, Port Melbourne, AU;

Peter Karellas, Reservoir, AU;

Guy Yeoman Krippner, Newtown, AU;

Brian Devlin Kelly, Ringwood East, AU;

Zemin Wu, Doncaster East, AU;

Pasquale Razzino, South Yarra, AU;

Sue Pallich, Yarraville, AU;

Inventors:

Benjamin James Boyd, Warrandyte, AU;

Lisa Michelle Kaminskas, Brunswick West, AU;

Christopher John Hamilton Porter, Port Melbourne, AU;

Peter Karellas, Reservoir, AU;

Guy Yeoman Krippner, Newtown, AU;

Brian Devlin Kelly, Ringwood East, AU;

Zemin Wu, Doncaster East, AU;

Pasquale Razzino, South Yarra, AU;

Sue Pallich, Yarraville, AU;

Assignee:

Starpharma Pty Limited, Melbourne, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a macromolecule having a controlled terminal group stoichiometry, the macromolecule including a surface layer, at least one subsurface layer and at least two terminal groups including: a first terminal group which is a residue of a pharmaceutically active agent, a derivative thereof or precursor therefor; and a second terminal group selected to modify the pharmacokinetics of the pharmaceutically active agent and/or macromolecule, wherein terminal group stoichiometry refers to the number and type of terminal groups.


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