The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2012
Filed:
Feb. 15, 2010
Charles A. Blum, Westbrook, CT (US);
Harry Brielmann, Guilford, CT (US);
Bertrand L. Chenard, Waterford, CT (US);
Xiaozhang Zheng, Branford, CT (US);
Charles A. Blum, Westbrook, CT (US);
Harry Brielmann, Guilford, CT (US);
Bertrand L. Chenard, Waterford, CT (US);
Xiaozhang Zheng, Branford, CT (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.