The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2012
Filed:
Mar. 02, 2011
Hans-peter Vornlocher, Cambridge, MA (US);
Ingo Roehl, Cambridge, MA (US);
Philipp Hadwiger, Cambridge, MA (US);
Tracy Stage Zimmermann, Cambridge, MA (US);
Muthiah Manoharan, Cambridge, MA (US);
Kallanthottathil G. Rajeev, Cambridge, MA (US);
Akin Akinc, Cambridge, MA (US);
Hans-Peter Vornlocher, Cambridge, MA (US);
Ingo Roehl, Cambridge, MA (US);
Philipp Hadwiger, Cambridge, MA (US);
Tracy Stage Zimmermann, Cambridge, MA (US);
Muthiah Manoharan, Cambridge, MA (US);
Kallanthottathil G. Rajeev, Cambridge, MA (US);
Akin Akinc, Cambridge, MA (US);
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
This invention relates to modified double-stranded oligoribonucleic acid (dsRNA) having improved stability in cells and biological fluids, and methods of making and identifying dsRNA having improved stability, and of using the dsRNA to inhibit the expression or function of a target gene.