The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
Feb. 18, 2004
Toshio Murakami, Kikuchi, JP;
Hirofumi Higuchi, Kikuchi, JP;
Keiichi Makizumi, Kikuchi, JP;
Toshihiro Maeda, Kikuchi, JP;
Hiroshi Mizokami, Kikuchi, JP;
Toshio Murakami, Kikuchi, JP;
Hirofumi Higuchi, Kikuchi, JP;
Keiichi Makizumi, Kikuchi, JP;
Toshihiro Maeda, Kikuchi, JP;
Hiroshi Mizokami, Kikuchi, JP;
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto-Ken, JP;
Abstract
A method of enhancing the efficacy of a monoclonal antibody preparation wherein antigens from patients are tested for their reactivity with the antibody. An amino acid sequence of an expressed protein is deuced from a nucleotide sequence determined by isolation and analysis of a target molecule gene in a biopsy from a patient. This is compared with the previously determined amino acid sequence recognized by the monoclonal antibody preparation in order to assess the fitness of patients for administration of the monoclonal antibody preparation.