The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2012

Filed:

Nov. 07, 2011
Applicants:

Patrick Albientz, St. Louis Neuweg, FR;

Jean-michel Grenet, Village Neuf, FR;

Rainer Hillenbrand, Shanghai, CN;

Francois Legay, Saint Louis, FR;

Peter Marbach, Therwil, CH;

Severine Marrony, Eschentzwiller, FR;

Judith Schaefer, Liestal/BL, CH;

Inventors:

Patrick Albientz, St. Louis Neuweg, FR;

Jean-Michel Grenet, Village Neuf, FR;

Rainer Hillenbrand, Shanghai, CN;

Francois Legay, Saint Louis, FR;

Peter Marbach, Therwil, CH;

Severine Marrony, Eschentzwiller, FR;

Judith Schaefer, Liestal/BL, CH;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/577 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invention also pertains to the respectively created binding agents and derivatives. Furthermore, drug monitoring assays using said binding agents for monitoring pharmaceutically active forms of said parent compound are provided.


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