The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
Jun. 24, 2009
Carin Borgvall, Stockholm, SE;
Ulrika Ericsson, Stockholm, SE;
Gustav Gilljam, Stockholm, SE;
Mats Jernberg, Stockholm, SE;
Stefan Winge, Stockholm, SE;
Carin Borgvall, Stockholm, SE;
Ulrika Ericsson, Stockholm, SE;
Gustav Gilljam, Stockholm, SE;
Mats Jernberg, Stockholm, SE;
Stefan Winge, Stockholm, SE;
Octapharma AG, Lachen, CH;
Abstract
A process of purifying or enriching coagulation FVIII employing chromatography comprising the steps of providing a fraction containing FVIII in an aqueous solution having a high ionic strength; contacting the fraction containing FVIII with a multimodal resin; optionally washing the multimodal resin having FVIII adsorbed with an aqueous washing buffer; eluting FVIII containing fractions by an aqueous elution buffer comprising at least one amino acid which is positively charged at pH 6 to 8; and optionally collecting FVIII containing fractions in purified or enriched form.