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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8329870 B1

PDFFull Text
Date of Patent:
Dec. 11, 2012

Filed:

Jan. 06, 2008

Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof

Applicants:

Boaz Amit, Kiryat Ono, IL;

Hilla Barkay-olami, Rishon Le Zion, IL;

Avner Yayon, Moshav Sitria, IL;

Inventors:

Boaz Amit, Kiryat Ono, IL;

Hilla Barkay-Olami, Rishon Le Zion, IL;

Avner Yayon, Moshav Sitria, IL;

Assignee:

Hepacore Ltd., Ness Ziona, IL;

Attorney:

Winston & Strawn LLP

Primary Examiner:

Marcela M Cordero Garcia

Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 38/00 (2006.01); A61K 35/14 (2006.01); A01N 43/04 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides water-soluble reactive esters of carboxy polysaccharides and derivatives thereof. The reactive carboxy polysaccharide derivatives are useful per se in aqueous solutions or specifically for the formation of water-soluble covalent fibrinogen conjugates. A preferred conjugate is a hyaluronic acid-fibrinogen conjugate and fibrin adhesive, clot or matrix derived from it. Methods of preparation and methods of use in tissue repair and regeneration are also disclosed.

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Amit, Boaz. (2012). Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof (U.S. Patent No. 8329870). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8329870

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