The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
Mar. 10, 2008
Tony Siu, Brookline, MA (US);
Jonathan Young, Southborough, MA (US);
Michael Altman, Cambridge, MA (US);
Alan Northrup, Reading, MA (US);
Ekaterina Kozina, Evanston, IL (US);
Christopher Dinsmore, Newton, MA (US);
David J. Guerin, Natick, MA (US);
Kevin A. Keenan, Newton, MA (US);
Joon O. Jung, Newton, MA (US);
Solomon Kattar, Arlington, MA (US);
Rachel N. Maccoss, Brookline, MA (US);
Tony Siu, Brookline, MA (US);
Jonathan Young, Southborough, MA (US);
Michael Altman, Cambridge, MA (US);
Alan Northrup, Reading, MA (US);
Ekaterina Kozina, Evanston, IL (US);
Christopher Dinsmore, Newton, MA (US);
David J. Guerin, Natick, MA (US);
Kevin A. Keenan, Newton, MA (US);
Joon O. Jung, Newton, MA (US);
Solomon Kattar, Arlington, MA (US);
Rachel N. MacCoss, Brookline, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The instant invention provides for compounds that inhibit JAK2 tyrosine kinase and/or PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting JAK2 tyrosine kinase activity and/or PDK1 kinase inhibitory activity by administering the compound to a patient in need of treatment or prevention of myeloproliferative disorders or cancer.