The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
May. 14, 2010
Eugene Gerner, Tucson, AZ (US);
Jason A. Zell, Dana Point, CA (US);
Christine Mclaren, Irvine, CA (US);
Frank Meyskens, Irvine, CA (US);
Hoda Anton-culver, Irvine, CA (US);
Patricia A. Thompson, Tucson, AZ (US);
Eugene Gerner, Tucson, AZ (US);
Jason A. Zell, Dana Point, CA (US);
Christine McLaren, Irvine, CA (US);
Frank Meyskens, Irvine, CA (US);
Hoda Anton-Culver, Irvine, CA (US);
Patricia A. Thompson, Tucson, AZ (US);
Arizona Board of Regents on Behalf of University of Arizona, Tucson, AZ (US);
The Regents of the University of California, a California Corporation, Oakland, CA (US);
Abstract
The present invention provides methods and kits a) for predicting colorectal cancer patient survival, as well as the survival of patients harboring other invasive cancers where cellular proliferation and carcinogenesis is linked, in part, to high levels of ODC activity and increased cellular polyamine contents, and b) for selecting the corresponding treatment options for such patients based on the allelic nucleotide sequence or SNP at position +316 of the ODC1 promoter gene as well as cancer treatment methods, in each case, which include the determination of the ODC1 promoter +316 position genotype, as a means to guide treatment selection.