The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
Jan. 30, 2009
Andrei G. Fadeev, Elmira, NY (US);
Jennifer Gehman, Painted Post, NY (US);
Arthur Winston Martin, Horseheads, NY (US);
Zara Melkoumian, Painted Post, NY (US);
Christopher B. Shogbon, Corning, NY (US);
David Michael Weber, St. Corniro, NY (US);
Yue Zhou, Horseheads, NY (US);
Andrei G. Fadeev, Elmira, NY (US);
Jennifer Gehman, Painted Post, NY (US);
Arthur Winston Martin, Horseheads, NY (US);
Zara Melkoumian, Painted Post, NY (US);
Christopher B. Shogbon, Corning, NY (US);
David Michael Weber, St. Corniro, NY (US);
Yue Zhou, Horseheads, NY (US);
Geron Corporation, Menlo Park, CA (US);
Abstract
Synthetic surfaces capable of supporting culture of undifferentiated human embryonic stem cells in a chemically defined medium include a swellable (meth)acrylate layer and a peptide conjugated to the swellable (meth)acrylate layer. The swellable (meth)acrylate layer may be formed by polymerizing monomers in a composition that includes hydroxyethyl methacrylate, 2-carboxyehylacrylate, and tetra(ethylene glycol) dimethacrylate. The conjugated peptide may include an amino acid sequence of XaaProGlnValThrArgGlyAspValPheThrMetPro, where n is an integer from 0 to 3 and where Xaa is any amino acid. Further, disclosed herein is a swellable (meth)acrylate synthetic surface which can be sterilized by gamma irradiation.