The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
Feb. 28, 2011
Kwok-yin Wong, Hong Kong, CN;
Yun Chung Leung, Hong Kong, CN;
Pak Ho Chan, Hong Kong, CN;
Wai Hong Chung, Hong Kong, CN;
Ka Yan Chow, Hong Kong, CN;
Ho Yin Chow, Hong Kong, CN;
Hon Man Leung, Hong Kong, CN;
Kwok-Yin Wong, Hong Kong, CN;
Yun Chung Leung, Hong Kong, CN;
Pak Ho Chan, Hong Kong, CN;
Wai Hong Chung, Hong Kong, CN;
Ka Yan Chow, Hong Kong, CN;
Ho yin Chow, Hong Kong, CN;
Hon Man Leung, Hong Kong, CN;
The Hong Kong Polytechnic University, Hong Kong, CN;
Abstract
Fast and simple method of detecting the presence of chloramphenicol, a harmful compound if present in food products. The method makes use of a mutant chloramphenicol acetyltransferase (CAT) and a fluorophore-linked chloramphenicol in a system where chloramphenicol and the fluorophore-linked chloramphenicol competes for the active site of the mutant CAT. Because the fluorophore-linked chloramphenicol reduces its fluorescence upon binding to the active site and vice versa increases its fluorescence upon being displaced from the active site by the presence of unmodified chloramphenicol in a sample, the increase of fluorescence caused by a testing sample indicates the presence of chloramphenicol.