The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
Aug. 31, 2010
Donmienne Doen Mun Leung, San Diego, CA (US);
Barbara Anne Swanson, Encinitas, CA (US);
Ying Tang, San Diego, CA (US);
Peng Luan, Livermore, CA (US);
Derrick Ryan Witcher, Fishers, IN (US);
Donmienne Doen Mun Leung, San Diego, CA (US);
Barbara Anne Swanson, Encinitas, CA (US);
Ying Tang, San Diego, CA (US);
Peng Luan, Livermore, CA (US);
Derrick Ryan Witcher, Fishers, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.