The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2012
Filed:
Aug. 11, 2008
Jose Mir, Rochester, NY (US);
Marek W. Kowarz, Henrietta, NY (US);
Kamal K. Sarbadhikari, Geneseo, NY (US);
Philip Ryan Ashe, Rochester, NY (US);
Jose Mir, Rochester, NY (US);
Marek W. Kowarz, Henrietta, NY (US);
Kamal K. Sarbadhikari, Geneseo, NY (US);
Philip Ryan Ashe, Rochester, NY (US);
Infotonics Technology Center, Inc., Canandaigua, NY (US);
Abstract
A method of determining a prothrombin time is disclosed. A mediator is applied to a stratum corneum. The stratum corneum is penetrated to allow the mediator to enter a region containing interstitial fluid and interact with at least one capillary, causing blood and/or blood components to leak from the at least one capillary into the region containing interstitial fluid. A characteristic affected by the blood and/or blood components is measured in the region containing interstitial fluid which correlates to the prothrombin time. A system for measuring prothrombin time is also disclosed. The system has a mediator, one or more microneedles, and a processor directly or indirectly coupled to the one or more microneedles and configured to determine a coagulation change in blood or blood components in a region around the one or more microneedles after the one or more microneedles penetrate a stratum corneum.