The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2012
Filed:
Aug. 16, 2010
Barry Hart, Palo Alto, CA (US);
Jeff Dener, Millbrae, CA (US);
Michael Green, Half Moon Bay, CA (US);
Michael Standen, Albany, OR (US);
Oldrich Kocian, Camelford, GB;
Barry Hart, Palo Alto, CA (US);
Jeff Dener, Millbrae, CA (US);
Michael Green, Half Moon Bay, CA (US);
Michael Standen, Albany, OR (US);
Oldrich Kocian, Camelford, GB;
ViroBay, Inc., Menlo Park, CA (US);
Abstract
The present invention relates to a process for the preparation of alkyl esters of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid, which are intermediates useful in the synthesis of (S)—N-(1-cyanocyclopropyl)-5-cyclopropyl-4,4-difluoro-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanamide and related compounds, which are compounds that are cysteine protease inhibitors.