The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2012

Filed:

Dec. 28, 2007
Applicants:

Chung-ming Hsieh, Newton, MA (US);

Bradford L. Mcrae, Northborough, MA (US);

Yuliya Kutskova, Northborough, MA (US);

John E. Memmott, Framingham, MA (US);

Michael Roguska, Ashland, MA (US);

Ian Tomlinson, Cambridge, GB;

Carrie Enever, Cambridge, GB;

Steven Grant, Ely, GB;

Mihriban Tuna, Cambridge, GB;

Inventors:

Chung-ming Hsieh, Newton, MA (US);

Bradford L. McRae, Northborough, MA (US);

Yuliya Kutskova, Northborough, MA (US);

John E. Memmott, Framingham, MA (US);

Michael Roguska, Ashland, MA (US);

Ian Tomlinson, Cambridge, GB;

Carrie Enever, Cambridge, GB;

Steven Grant, Ely, GB;

Mihriban Tuna, Cambridge, GB;

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides an isolated, dual-specific antibody, or an antigen-binding portion thereof, which is specific for human IL-1α and human IL-1β. The dual specific antibodies of the invention also neutralize both human IL-1α and human IL-1β. The invention also provides domain antibodies (dAbs) specific for human IL-1α and human IL-1β.


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