The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2012

Filed:

Mar. 11, 2010
Applicants:

Henner Knust, Rheinfelden, DE;

Anja Limberg, Basel, CH;

Matthias Nettekoven, Grenzach-Wyhlen, DE;

Hasane Ratni, Habsheim, FR;

Claus Riemer, Freiburg, DE;

Walter Vifian, Gelterkinden, CH;

Inventors:

Henner Knust, Rheinfelden, DE;

Anja Limberg, Basel, CH;

Matthias Nettekoven, Grenzach-Wyhlen, DE;

Hasane Ratni, Habsheim, FR;

Claus Riemer, Freiburg, DE;

Walter Vifian, Gelterkinden, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07D 413/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present application relates to compounds of formula wherein the definitions are as described herein. The present compounds are high potential NK-3 receptor antagonists that are useful for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).


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