The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2012
Filed:
May. 22, 2009
Anjali Pandey, Fremont, CA (US);
Robert M. Scarborough, Half Moon Bay, CA (US);
Kenji Matsuno, Tokyo, JP;
Michio Ichimura, Tokyo, JP;
Yuji Nomoto, Shizuoka, JP;
Shinichi Ide, Tokyo, JP;
Eiji Tsukuda, Tokyo, JP;
Junko Sasaki, Akita, JP;
Shoji Oda, Tokyo, JP;
Anjali Pandey, Fremont, CA (US);
Robert M. Scarborough, Half Moon Bay, CA (US);
Kenji Matsuno, Tokyo, JP;
Michio Ichimura, Tokyo, JP;
Yuji Nomoto, Shizuoka, JP;
Shinichi Ide, Tokyo, JP;
Eiji Tsukuda, Tokyo, JP;
Junko Sasaki, Akita, JP;
Shoji Oda, Tokyo, JP;
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Kyowa Hakko Kogyo Co., Ltd., Tokyo, JP;
Abstract
The present invention relates to nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof which have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention is also related to a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases. In a particular aspect the present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof which inhibit phosphorylation of a PDGF receptor to hinder abnormal cell growth and cell wandering, and a method for preventing or treating cell-proliferative diseases such as arteriosclerosis, vascular reobstruction, cancer and glomerulosclerosis.