The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2012
Filed:
Dec. 13, 2002
Jack J. Hawiger, Nashville, TN (US);
Daniel Robinson, Lexington, KY (US);
Ruth Ann Veach, Brentwood, TN (US);
Xue Yan Liu, Nashville, TN (US);
Danya Liu, Nashville, TN (US);
Sheila Downs, Nashville, TN (US);
Robert D. Collins, Nashville, TN (US);
Yao-zhong Lin, Nashville, TN (US);
Jack J. Hawiger, Nashville, TN (US);
Daniel Robinson, Lexington, KY (US);
Ruth Ann Veach, Brentwood, TN (US);
Xue Yan Liu, Nashville, TN (US);
Danya Liu, Nashville, TN (US);
Sheila Downs, Nashville, TN (US);
Robert D. Collins, Nashville, TN (US);
Yao-Zhong Lin, Nashville, TN (US);
Vanderbilt University, Nashville, TN (US);
Abstract
The present invention relates to the delivery of biologically active molecules, such as peptides, nucleic acids and therapeutic agents, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized for purposes such as peptide therapy, gene transfer, and antisense therapy to regulate and/or eradicate systemic inflammatory response syndromes such as endotoxic shock.