The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2012
Filed:
May. 08, 2008
Douglas E. Brough, Gaithersburg, MD (US);
Joseph T. Bruder, Ijamsville, MD (US);
C. Richter King, New York, NY (US);
Marvin J. Grubman, Southold, NY (US);
John G. Neilan, Wethersfield, CT (US);
Douglas E. Brough, Gaithersburg, MD (US);
Joseph T. Bruder, Ijamsville, MD (US);
C. Richter King, New York, NY (US);
Marvin J. Grubman, Southold, NY (US);
John G. Neilan, Wethersfield, CT (US);
GenVec, Inc., Gaithersburg, MD (US);
Abstract
The invention is directed to an adenoviral vector comprising at least one nucleic acid sequence encoding anantigen and/or a cytokine operably linked to a promoter. The adenoviral vector is replication-deficient and requires at most complementation of both the E1 region and the E4 region of the adenoviral genome for propagation. The invention also is directed to a method of inducing an immune response in a mammal comprising administering to the mammal a composition comprising the aforementioned adenoviral vector.